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Rozerem Sleep Aid



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Rozerem™ (Ramelteon)

Rozerem is a new sleep aid with unique benefits.

    • Rozerem is safe and non-addictive
    • Rozerem can be prescribed for long-term use

Rozerem is different from other sleep aids. Rozerem is the first prescription insomnia medication with a new therapeutic mechanism in 35 years.

What is Rozerem™?
Rozerem is a new sleeping pill made by Japanese drug company Takeda. Rozerem was approved July 22nd, 2005. It has been available since September 27th, 2005.

How is rozerem different from other sleep aids?
Rozerem works by stimulating the so-called "melatonin receptors" in your brain. (The fancy name for melatonin receptors are "the MT1 receptor" and the "MT2 receptor"). These receptors regulate sleep by making sure that your body's internal clock is running correctly. This internal clock tells you when to get tired. That is why a normal person gets tired at night and wakes up in the morning. When this clock is out of whack (as when you have insomnia) you have trouble falling asleep.

What about Rozerem side effects?
Takeda conducted a 4,251 patient trial to evaluate Rozerem for side effects. Some of these test subjects took Rozerem for as long as one year. Rozerem was found to be generally safe and well tolerated. The most common side effects for Rozerem are sleepiness (duh), fatigue, dizziness and headache. These side effects are rare.

Can Rozerem be taken by pregnant women?
Rozerem is pregnancy category "C" (just like Lunesta and Sonata). Category "C" means that there are no adequate and well controlled studies regarding the use of Rozerem during pregnancy. It should only be used if the benefits outweigh the potential risk to the fetus. In other words, it's probably not a good idea in most cases

Will I feel drowsy the next day?
When you wake up from a Rozerem induced sleep, you will have no after effects unlike other sleeping pills.

Is Rozerem safe for long term use?
Yes. Rozerem is safe for long term use. Also, Rozerem has a very low abuse potential -- drug addicts cannot get high from Rozerem like they can with other sleeping pills.

Is Rozerem a controlled substance?
Certain medications are classified as controlled substances in the US due to differences in prescribing regulations that apply to medical professionals in that country. Rozerem is not as controlled substance. This means it is easier for the doctor to prescribe.

What are the precautions for taking Rozerem?
Rozerem should not be used in patients with hypersensitivity to ramelteon or any components of the formulation. Rozerem has not been studied in subjects with severe sleep apnea or severe COPD and is not recommended for use in those populations. Patients should be advised to exercise caution if they consume alcohol in combination with Rozerem. Rozerem is safe to take if you have kidney disease. Even patients with severe renal impairment can safely take Rozerem. But Rozerem should be used with severe caution in patients with liver disease. Rozerem should not be used by patients with severe hepatic impairment, or in patients in combination with fluvoxamine.

What are the instructions for use of Rozerem?
Rozerem should be taken within 30 minutes before going to bed and activities should be confined to those necessary to prepare for bed. Rozerem should not be taken with or immediately after a high-fat meal. Engaging in hazardous activities that require concentration (such as operating a motor vehicle or heavy machinery) after taking Rozerem should be avoided.

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